Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF4B All Species: 18.18
Human Site: S155 Identified Species: 66.67
UniProt: P23588 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23588 NP_001408.2 611 69151 S155 D S L L S A L S L N E E S L G
Chimpanzee Pan troglodytes XP_001142097 610 69033 S155 D S L L S A L S L N E E S L G
Rhesus Macaque Macaca mulatta XP_001101380 607 68582 S155 D S L L S A L S L N E E S L G
Dog Lupus familis XP_534793 612 69170 S155 D S L L S A L S L N E E S L G
Cat Felis silvestris
Mouse Mus musculus Q8BGD9 611 68821 S155 D S L L S A L S L N E E S L G
Rat Rattus norvegicus Q5XI72 248 27306
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393068 502 57369 L99 Y E V D E T Y L T E F F A N M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 96 N.A. 94.2 20.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 30.9 N.A. N.A.
Protein Similarity: 100 99.8 98.5 97.7 N.A. 96.5 28.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 45.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 72 0 0 0 0 0 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 72 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 15 0 0 15 0 0 0 0 15 72 72 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 15 15 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 72 72 0 0 72 15 72 0 0 0 0 72 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 0 72 0 0 0 15 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 72 0 0 72 0 0 72 0 0 0 0 72 0 0 % S
% Thr: 0 0 0 0 0 15 0 0 15 0 0 0 0 0 0 % T
% Val: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _